# Reading list

> Chelsea Skin Clinic reading list — The Chelsea Skin Clinic reading list covers KPV antimicrobial cultures, inflammatory signals, wound gels and human skin-cell experiments.

Microbial cultures, host-cell responses and the materials used to bring a peptide to tissue.

## Cultures, cells and a wound gel

The [antimicrobial culture paper](https://pubmed.ncbi.nlm.nih.gov/10670585/) starts this collection. Its organisms give the word growth a particular object. The macrophage and keratinocyte studies then put the host’s own cells into the picture.

[The macrophage and peritonitis experiment](https://pubmed.ncbi.nlm.nih.gov/12750433/) separates two responses: KPV reduced polymorphonuclear leukocyte accumulation in mice with crystal-induced peritonitis, while it did not suppress cytokine release in cultured macrophages in vitro. It is useful resistance to a tidy account of KPV. The hydrogel papers add questions about the preparation carrying the peptide.

## References

[1] Antimicrobial effects of alpha-MSH peptides https://pubmed.ncbi.nlm.nih.gov/10670585/
[2] Alpha-melanocyte-stimulating hormone and related tripeptides: biochemistry, antiinflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseases https://pubmed.ncbi.nlm.nih.gov/18612139/
[3] In situ mucoadhesive hydrogel capturing tripeptide KPV: the anti-inflammatory, antibacterial and repairing effect https://pubmed.ncbi.nlm.nih.gov/34846053/
[4] The synthetic melanocortin (CKPV)2 exerts anti-fungal and anti-inflammatory effects against Candida albicans vaginitis via inducing macrophage M2 polarization https://pubmed.ncbi.nlm.nih.gov/23457491/
[5] Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptides https://pubmed.ncbi.nlm.nih.gov/12750433/
[6] PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation https://pubmed.ncbi.nlm.nih.gov/18061177/
[7] Self-Cross-Linked Hydrogel of Cysteamine-Grafted gamma-Polyglutamic Acid Stabilized Tripeptide KPV for Treating Inflammatory Bowel Disease https://pubmed.ncbi.nlm.nih.gov/34547895/
[8] Alpha-melanocyte-stimulating hormone, MSH 11-13 KPV and adrenocorticotropic hormone signalling in human keratinocyte cells https://pubmed.ncbi.nlm.nih.gov/15102092/
[9] Lysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation https://pubmed.ncbi.nlm.nih.gov/40073467/

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At Chelsea Skin Clinic I cultivate questions from published research; this is an editorial publication, with no medical advice or clinical business behind its name.
